16.11.2025 16:05 • United States • NFL 2025/2026

Arizona Cardinals - San Francisco 49ers Predictions and Betting Tips

Arizona Cardinals versus San Francisco 49ers takes place at 16:05 on 16.11.2025.

Arizona Cardinals

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San Francisco 49ers

Choose your bet!

Check out the latest Arizona Cardinals vs San Francisco 49ers betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "San Francisco 49ers" with odds of 1.73 from 1 out of 1 users.

The hottest bet types to choose from:

Home Away

San Francisco 49ers

100%

1 out of 1 tipsters

JohnnyBet’s Betting Tips for Arizona Cardinals - San Francisco 49ers by tipsters profit

Our most profitable tipster for this event, krex22 (ranking at 2201 in overall Profit) is predicting 7.3 in profit by staking 10 on San Francisco 49ers (1.73) in Home Away bet.

krex22

Rank: 2201/2196

Profit: -993.04

10/10

Estimated profit 7.30

JohnnyBet’s Betting Tips for Arizona Cardinals - San Francisco 49ers by tipsters yield

If you trust yield more than profit, krex22 (with -21.11% overall yield) gives a prediction to get 7.3 profit by staking 10 on San Francisco 49ers (1.73) in Home Away market.

krex22

Rank: 1655/2196

Yield: -21.11%

10/10

Estimated profit 7.30

JohnnyBet’s Betting Tips for Arizona Cardinals - San Francisco 49ers by tipsters ODI

These tipsters know how to find best-value bets! krex22, with an ODI parameter of -177.63 stakes 10 on odds of 1.73 for San Francisco 49ers in Home Away market. It can bag a 7.3 profit.

krex22

Rank: 2253/2196

ODI: -177.63

10/10

Estimated profit 7.30

The best AI betting tips for Arizona Cardinals vs San Francisco 49ers

What result for Arizona Cardinals vs San Francisco 49ers does artificial intelligence predict? AI calculates that the most likely outcome is a bet on San Francisco 49ers in the Home Away market, at odds of 1.73, with a stake of 10, from krex22.

krex22

10/10

Estimated profit 7.30

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Arizona Cardinals vs San Francisco 49ers game. The top prediction, with 100% of the votes is a win for San Francisco 49ers (odds of 1.73). A victory for Arizona Cardinals (2.25) has collected 0% of the votes.

1 0%

2 100%

Arizona Cardinals vs San Francisco 49ers Betting Tips

Tip 1:

Odds 1.73 for San Francisco 49ers (Home Away)