05.10.2025 20:20 • United States • NFL 2025/2026

Buffalo Bills - New England Patriots Predictions and Betting Tips

Buffalo Bills versus New England Patriots takes place at 20:20 on 05.10.2025.

Buffalo Bills

—

New England Patriots

Choose your bet!

Check out the latest Buffalo Bills vs New England Patriots betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "Buffalo Bills" with odds of 1.26 from 1 out of 1 users.

The hottest bet types to choose from:

Home Away

Buffalo Bills

100%

1 out of 1 tipsters

JohnnyBet’s Betting Tips for Buffalo Bills - New England Patriots by tipsters profit

Our most profitable tipster for this event, Deibis Mendez (ranking at 193 in overall Profit) is predicting 0.78 in profit by staking 3 on Buffalo Bills (1.26) in Home Away bet.

Deibis Mendez

Rank: 193/1663

Profit: 24.07

3/10

Estimated profit 0.78

JohnnyBet’s Betting Tips for Buffalo Bills - New England Patriots by tipsters yield

If you trust yield more than profit, Deibis Mendez (with 6.84% overall yield) gives a prediction to get 0.78 profit by staking 3 on Buffalo Bills (1.26) in Home Away market.

Deibis Mendez

Rank: 323/1663

Yield: 6.84%

3/10

Estimated profit 0.78

JohnnyBet’s Betting Tips for Buffalo Bills - New England Patriots by tipsters ODI

These tipsters know how to find best-value bets! Deibis Mendez , with an ODI parameter of -0.45 stakes 3 on odds of 1.26 for Buffalo Bills in Home Away market. It can bag a 0.78 profit.

Deibis Mendez

Rank: 1020/1663

ODI: -0.45

3/10

Estimated profit 0.78

The best AI betting tips for Buffalo Bills vs New England Patriots

What result for Buffalo Bills vs New England Patriots does artificial intelligence predict? AI calculates that the most likely outcome is a bet on Buffalo Bills in the Home Away market, at odds of 1.26, with a stake of 3, from Deibis Mendez .

Deibis Mendez

3/10

Estimated profit 0.78

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Buffalo Bills vs New England Patriots game. The top prediction, with 100% of the votes, is a win for Buffalo Bills (odds of 1.26). While, a victory for New England Patriots (4.41) has collected 0% of the votes.

1 100%

2 0%

bet365

How to watch Buffalo Bills vs New England Patriots Live Stream

You can watch Buffalo Bills vs New England Patriots live at 20:20 on 2025-10-05 thanks to bet365 live streaming services. Check the available options on the global listing below.

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Buffalo Bills vs New England Patriots Betting Tips

Tip 1:

Odds 1.26 for Buffalo Bills (Home Away)