28.09.2025 13:00 • United States • NFL 2025/2026

Buffalo Bills - New Orleans Saints Predictions and Betting Tips

Buffalo Bills versus New Orleans Saints takes place at 13:00 on 28.09.2025.

Buffalo Bills

—

New Orleans Saints

Choose your bet!

Check out the latest Buffalo Bills vs New Orleans Saints betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "New Orleans Saints" with odds of 11.73 from 1 out of 1 users.

The hottest bet types to choose from:

Home Away

New Orleans Saints

100%

1 out of 1 tipsters

JohnnyBet’s Betting Tips for Buffalo Bills - New Orleans Saints by tipsters profit

Our most profitable tipster for this event, Gatita (ranking at 1427 in overall Profit) is predicting 42.92 in profit by staking 4 on New Orleans Saints (11.73) in Home Away bet.

Gatita

Rank: 1427/1568

Profit: -329.54

4/10

Estimated profit 42.92

JohnnyBet’s Betting Tips for Buffalo Bills - New Orleans Saints by tipsters yield

If you trust yield more than profit, Gatita (with -5.7% overall yield) gives a prediction to get 42.92 profit by staking 4 on New Orleans Saints (11.73) in Home Away market.

Gatita

Rank: 780/1568

Yield: -5.7%

4/10

Estimated profit 42.92

JohnnyBet’s Betting Tips for Buffalo Bills - New Orleans Saints by tipsters ODI

These tipsters know how to find best-value bets! Gatita, with an ODI parameter of -73.54 stakes 4 on odds of 11.73 for New Orleans Saints in Home Away market. It can bag a 42.92 profit.

Gatita

Rank: 1540/1568

ODI: -73.54

4/10

Estimated profit 42.92

The best AI betting tips for Buffalo Bills vs New Orleans Saints

What result for Buffalo Bills vs New Orleans Saints does artificial intelligence predict? AI calculates that the most likely outcome is a bet on New Orleans Saints in the Home Away market, at odds of 11.73, with a stake of 4, from Gatita.

Gatita

4/10

Estimated profit 42.92

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Buffalo Bills vs New Orleans Saints game. The top prediction, with 100% of the votes is a win for New Orleans Saints (odds of 11.73). A victory for Buffalo Bills (1.08) has collected 0% of the votes.

1 0%

2 100%

bet365

How to watch Buffalo Bills vs New Orleans Saints Live Stream

You can watch Buffalo Bills vs New Orleans Saints live at 13:00 on 2025-09-28 thanks to bet365 live streaming services. Check the available options on the global listing below.

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Buffalo Bills vs New Orleans Saints Betting Tips

Tip 1:

Odds 11.73 for New Orleans Saints (Home Away)