26.10.2025 13:00 • United States • NFL 2025/2026

Carolina Panthers - Buffalo Bills Predictions and Betting Tips

Carolina Panthers versus Buffalo Bills takes place at 13:00 on 26.10.2025.

Carolina Panthers

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Buffalo Bills

Choose your bet!

Check out the latest Carolina Panthers vs Buffalo Bills betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "Carolina Panthers" with odds of 4.32 from 1 out of 1 users.

The hottest bet types to choose from:

Home Away

Carolina Panthers

100%

1 out of 1 tipsters

JohnnyBet’s Betting Tips for Carolina Panthers - Buffalo Bills by tipsters profit

Our most profitable tipster for this event, José Miguel varela (ranking at 1608 in overall Profit) is predicting 26.56 in profit by staking 8 on Carolina Panthers (4.32) in Home Away bet.

José Miguel varela

Rank: 1608/1946

Profit: -129.36

8/10

Estimated profit 26.56

JohnnyBet’s Betting Tips for Carolina Panthers - Buffalo Bills by tipsters yield

If you trust yield more than profit, José Miguel varela (with -19.02% overall yield) gives a prediction to get 26.56 profit by staking 8 on Carolina Panthers (4.32) in Home Away market.

José Miguel varela

Rank: 1448/1946

Yield: -19.02%

8/10

Estimated profit 26.56

JohnnyBet’s Betting Tips for Carolina Panthers - Buffalo Bills by tipsters ODI

These tipsters know how to find best-value bets! José Miguel varela, with an ODI parameter of -7.58 stakes 8 on odds of 4.32 for Carolina Panthers in Home Away market. It can bag a 26.56 profit.

José Miguel varela

Rank: 1724/1946

ODI: -7.58

8/10

Estimated profit 26.56

The best AI betting tips for Carolina Panthers vs Buffalo Bills

What result for Carolina Panthers vs Buffalo Bills does artificial intelligence predict? AI calculates that the most likely outcome is a bet on Carolina Panthers in the Home Away market, at odds of 4.32, with a stake of 8, from José Miguel varela.

José Miguel varela

8/10

Estimated profit 26.56

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Carolina Panthers vs Buffalo Bills game. The top prediction, with 100% of the votes, is a win for Carolina Panthers (odds of 4.32). While, a victory for Buffalo Bills (1.25) has collected 0% of the votes.

1 100%

2 0%

Carolina Panthers vs Buffalo Bills Betting Tips

Tip 1:

Odds 4.32 for Carolina Panthers (Home Away)