12.09.2025 19:10 United States MLB 2025

Cleveland Guardians - Chicago White Sox Predictions and Betting Tips

Cleveland Guardians versus Chicago White Sox takes place at 19:10 on 12.09.2025.

Cleveland Guardians
Chicago White Sox
Chicago White Sox

Choose your bet!

Check out the latest Cleveland Guardians vs Chicago White Sox betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "Chicago White Sox" with odds of 2.42 from 4 out of 6 users. Another popular betting line is "Asian Handicap (-1.5)" with a "Cleveland Guardians (-1.5), money back on draw" result (odds of 2.25) from 100%.

The hottest bet types to choose from:

Home Away
Chicago White Sox
67%
4 out of 6 tipsters
Over/Under 8.5
Over
100%
2 out of 2 tipsters
Asian Handicap (-1.5)
Cleveland Guardians (-1.5), money back on draw
100%
2 out of 2 tipsters

JohnnyBet’s Betting Tips for Cleveland Guardians - Chicago White Sox by tipsters profit

Our most profitable tipster for this event, edoard travieso 85 (ranking at 770 in overall Profit) is predicting 14.2 in profit by staking 10 on Chicago White Sox (2.42) in Home Away bet. kevyn rojas on the other hand (ranking at 954), gives a tip on 2.29 for Chicago White Sox (Home Away) by staking 10 to get an estimated profit of 12.9. The third most profitable tipster (1065 this season), Yossarian estimates to get 13.1 in profit by staking 10 on 2.31 for Cleveland Guardians (-1.5), money back on draw in Asian Handicap (-1.5) market.

edoard travieso 85
edoard travieso 85
Rank: 770/1418
Profit: -24.28
Home Away
+142 for Chicago White Sox
10/10
Estimated profit 14.20
kevyn rojas
kevyn rojas
Rank: 954/1418
Profit: -58.58
Home Away
+129 for Chicago White Sox
10/10
Estimated profit 12.90
Yossarian
Yossarian
Rank: 1065/1418
Profit: -102.48
Asian Handicap (-1.5)
+131 for Cleveland Guardians (-1.5), money back on draw
10/10
Estimated profit 13.10
yonhanier
yonhanier
Rank: 1167/1418
Profit: -167.92
Home Away
+127 for Chicago White Sox
10/10
Estimated profit 12.70
Emi0512
Emi0512
Rank: 1210/1418
Profit: -203.16
Home Away
-161 for Cleveland Guardians
4/10
Estimated profit 2.48
1 2 3

JohnnyBet’s Betting Tips for Cleveland Guardians - Chicago White Sox by tipsters yield

If you trust yield more than profit, edoard travieso 85 (with -0.63% overall yield) gives a prediction to get 14.2 profit by staking 10 on Chicago White Sox (2.42) in Home Away market. Then, there is Yossarian with -1.04% yield. Giving a tip with 10 stake for Cleveland Guardians (-1.5), money back on draw (2.31) in Asian Handicap (-1.5). The estimated profit is 13.1. Tiresia (-2.5% yield) picked 2.42 for Chicago White Sox in Home Away market. Staking 10 will bring 14.2 profit if correct.

edoard travieso 85
edoard travieso 85
Rank: 445/1418
Yield: -0.63%
Home Away
+142 for Chicago White Sox
10/10
Estimated profit 14.20
Yossarian
Yossarian
Rank: 468/1418
Yield: -1.04%
Asian Handicap (-1.5)
+131 for Cleveland Guardians (-1.5), money back on draw
10/10
Estimated profit 13.10
Tiresia
Tiresia
Rank: 529/1418
Yield: -2.5%
Home Away
+142 for Chicago White Sox
10/10
Estimated profit 14.20
yonhanier
yonhanier
Rank: 553/1418
Yield: -3.01%
Home Away
+127 for Chicago White Sox
10/10
Estimated profit 12.70
faro2013
faro2013
Rank: 641/1418
Yield: -4.87%
Home Away
-141 for Cleveland Guardians
10/10
Estimated profit 7.10
1 2 3

JohnnyBet’s Betting Tips for Cleveland Guardians - Chicago White Sox by tipsters ODI

These tipsters know how to find best-value bets! AMAYA, with an ODI parameter of 30.39 stakes 10 on odds of 2.23 for Over in Over/Under 8.5 market. It can bag a 12.3 profit. Emi0512 (ODI: 14.63) placing betting tip to get 2.48 profit by putting 4 on Cleveland Guardians (1.62) in Home Away bet. Third in overall ranking (ODI: 12.52), edoard travieso 85, chose Home Away market by going with an 10 stake on odds of 2.42 for Chicago White Sox, estimating profit of 14.2.

AMAYA
AMAYA
Rank: 85/1418
ODI: 30.39
Over/Under 8.5
+123 for Over
10/10
Estimated profit 12.30
Emi0512
Emi0512
Rank: 115/1418
ODI: 14.63
Home Away
-161 for Cleveland Guardians
4/10
Estimated profit 2.48
edoard travieso 85
edoard travieso 85
Rank: 121/1418
ODI: 12.52
Home Away
+142 for Chicago White Sox
10/10
Estimated profit 14.20
kevyn rojas
kevyn rojas
Rank: 1258/1418
ODI: -15.85
Home Away
+129 for Chicago White Sox
10/10
Estimated profit 12.90
yonhanier
yonhanier
Rank: 1345/1418
ODI: -47.45
Home Away
+127 for Chicago White Sox
10/10
Estimated profit 12.70
1 2 3

The best AI betting tips for Cleveland Guardians vs Chicago White Sox

What result for Cleveland Guardians vs Chicago White Sox does artificial intelligence predict? AI calculates that the most likely outcome is a bet on Cleveland Guardians in the Home Away market, at odds of 1.62, with a stake of 4, from Emi0512. A bet on Over (1.89) in the Over/Under 7.5 market with a stake of 10 from faro2013 is another AI favourite. The third most likely winning bet according to the algorithm is Cleveland Guardians (-1.5), money back on draw in the Asian Handicap (-1.5) market, on which Yossarian is placing 10 at odds of 2.31.

Emi0512
Emi0512
Home Away
-161 for Cleveland Guardians
4/10
Estimated profit 2.48
faro2013
faro2013
Over/Under 7.5
-112 for Over
10/10
Estimated profit 8.90
Yossarian
Yossarian
Asian Handicap (-1.5)
+131 for Cleveland Guardians (-1.5), money back on draw
10/10
Estimated profit 13.10
Tiresia
Tiresia
Home Away
+142 for Chicago White Sox
10/10
Estimated profit 14.20
edoard travieso 85
edoard travieso 85
Home Away
+142 for Chicago White Sox
10/10
Estimated profit 14.20
1 2 3

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Cleveland Guardians vs Chicago White Sox game. The top prediction, with 67% of the votes is a win for Chicago White Sox (odds of 2.42). A victory for Cleveland Guardians (1.62) has collected 33% of the votes.

1 33%
2 67%
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Cleveland Guardians vs Chicago White Sox Betting Tips

Tip 1:
Odds 2.42 for Chicago White Sox (Home Away)
Tip 2:
Odds 2.23 for Over (Over/Under 8.5)
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