21.05.2026 13:10 United States MLB 2026

Detroit Tigers - Cleveland Guardians Predictions and Betting Tips

Detroit Tigers versus Cleveland Guardians takes place at 13:10 on 21.05.2026.

Detroit Tigers
Detroit Tigers
Cleveland Guardians

Choose your bet!

Check out the latest Detroit Tigers vs Cleveland Guardians betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "Cleveland Guardians" with odds of -101 from 4 out of 4 users. Another popular betting line is "Asian Handicap (1.5)" with a "Cleveland Guardians (-1.5), money back on draw" result (odds of +168) from 100%.

The hottest bet types to choose from:

Home Away
Cleveland Guardians
100%
4 out of 4 tipsters
Over/Under 8.5
Under
100%
1 out of 1 tipsters
Asian Handicap (1.5)
Cleveland Guardians (-1.5), money back on draw
100%
1 out of 1 tipsters

JohnnyBet’s Betting Tips for Detroit Tigers - Cleveland Guardians by tipsters profit

Our most profitable tipster for this event, Bayern007 (ranking at 10 in overall Profit) is predicting 5.7 in profit by staking 10 on Under (-175) in Over/Under 8.5 bet. Sylwester Zalewski on the other hand (ranking at 24), gives a tip on -101 for Cleveland Guardians (Home Away) by staking 10 to get an estimated profit of 9.9. The third most profitable tipster (239 this season), IMPERIO estimates to get 16.8 in profit by staking 10 on +168 for Cleveland Guardians (-1.5), money back on draw in Asian Handicap (1.5) market.

Bayern007
Bayern007
Rank: 10/4079
Profit: 349.64
Over/Under 8.5
-175 for Under
10/10
Estimated profit 5.70
Sylwester Zalewski
Rank: 24/4079
Profit: 273.74
Home Away
-101 for Cleveland Guardians
10/10
Estimated profit 9.90
IMPERIO
IMPERIO
Rank: 239/4079
Profit: 35.74
Asian Handicap (1.5)
+168 for Cleveland Guardians (-1.5), money back on draw
10/10
Estimated profit 16.80
soap_mactavish
soap_mactavish
Rank: 4237/4079
Profit: -788.7
Home Away
+103 for Cleveland Guardians
10/10
Estimated profit 10.30
viveiron
viveiron
Rank: 4348/4079
Profit: -1496.95
Home Away
+101 for Cleveland Guardians
10/10
Estimated profit 10.10
1 2

JohnnyBet’s Betting Tips for Detroit Tigers - Cleveland Guardians by tipsters yield

If you trust yield more than profit, Sylwester Zalewski (with 15.92% overall yield) gives a prediction to get 9.9 profit by staking 10 on Cleveland Guardians (-101) in Home Away market. Then, there is Bayern007 with 3.3% yield. Giving a tip with 10 stake for Under (-175) in Over/Under 8.5. The estimated profit is 5.7. IMPERIO (2.66% yield) picked +168 for Cleveland Guardians (-1.5), money back on draw in Asian Handicap (1.5) market. Staking 10 will bring 16.8 profit if correct.

Sylwester Zalewski
Rank: 774/4079
Yield: 15.92%
Home Away
-101 for Cleveland Guardians
10/10
Estimated profit 9.90
Bayern007
Bayern007
Rank: 1097/4079
Yield: 3.3%
Over/Under 8.5
-175 for Under
10/10
Estimated profit 5.70
IMPERIO
IMPERIO
Rank: 1133/4079
Yield: 2.66%
Asian Handicap (1.5)
+168 for Cleveland Guardians (-1.5), money back on draw
10/10
Estimated profit 16.80
soap_mactavish
soap_mactavish
Rank: 1533/4079
Yield: -2.11%
Home Away
+103 for Cleveland Guardians
10/10
Estimated profit 10.30
viveiron
viveiron
Rank: 1678/4079
Yield: -3.1%
Home Away
+101 for Cleveland Guardians
10/10
Estimated profit 10.10
1 2

JohnnyBet’s Betting Tips for Detroit Tigers - Cleveland Guardians by tipsters ODI

These tipsters know how to find best-value bets! Sylwester Zalewski, with an ODI parameter of 5.26 stakes 10 on odds of -101 for Cleveland Guardians in Home Away market. It can bag a 9.9 profit. IMPERIO (ODI: -9.19) placing betting tip to get 16.8 profit by putting 10 on Cleveland Guardians (-1.5), money back on draw (+168) in Asian Handicap (1.5) bet. Third in overall ranking (ODI: -38.95), Bayern007, chose Over/Under 8.5 market by going with an 10 stake on odds of -175 for Under, estimating profit of 5.7.

Sylwester Zalewski
Rank: 508/4079
ODI: 5.26
Home Away
-101 for Cleveland Guardians
10/10
Estimated profit 9.90
IMPERIO
IMPERIO
Rank: 3795/4079
ODI: -9.19
Asian Handicap (1.5)
+168 for Cleveland Guardians (-1.5), money back on draw
10/10
Estimated profit 16.80
Bayern007
Bayern007
Rank: 4111/4079
ODI: -38.95
Over/Under 8.5
-175 for Under
10/10
Estimated profit 5.70
soap_mactavish
soap_mactavish
Rank: 4360/4079
ODI: -277.54
Home Away
+103 for Cleveland Guardians
10/10
Estimated profit 10.30
viveiron
viveiron
Rank: 4441/4079
ODI: -1223.35
Home Away
+101 for Cleveland Guardians
10/10
Estimated profit 10.10
1 2

The best AI betting tips for Detroit Tigers vs Cleveland Guardians

What result for Detroit Tigers vs Cleveland Guardians does artificial intelligence predict? AI calculates that the most likely outcome is a bet on Under in the Over/Under 8.5 market, at odds of -175, with a stake of 10, from Bayern007. A bet on Cleveland Guardians (-101) in the Home Away market with a stake of 10 from Sylwester Zalewski is another AI favourite. The third most likely winning bet according to the algorithm is Cleveland Guardians (-1.5), money back on draw in the Asian Handicap (1.5) market, on which IMPERIO is placing 10 at odds of +168.

Over/Under 8.5
-175 for Under
10/10
Estimated profit 5.70
Home Away
-101 for Cleveland Guardians
10/10
Estimated profit 9.90
Asian Handicap (1.5)
+168 for Cleveland Guardians (-1.5), money back on draw
10/10
Estimated profit 16.80
Home Away
+103 for Cleveland Guardians
10/10
Estimated profit 10.30
Home Away
+101 for Cleveland Guardians
10/10
Estimated profit 10.10
1 2

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Detroit Tigers vs Cleveland Guardians game. The top prediction, with 100% of the votes is a win for Cleveland Guardians (odds of -101). A victory for Detroit Tigers (-114) has collected 0% of the votes.

1 0%
2 100%

Detroit Tigers vs Cleveland Guardians Betting Tips

Tip 1:
Odds -175 for Under (Over/Under 8.5)
Tip 2:
Odds -101 for Cleveland Guardians (Home Away)
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