09.11.2025 16:25 United States NFL 2025/2026

San Francisco 49ers - Los Angeles Rams Predictions and Betting Tips

San Francisco 49ers versus Los Angeles Rams takes place at 16:25 on 09.11.2025.

San Francisco 49ers
San Francisco 49ers
Los Angeles Rams
Los Angeles Rams

Choose your bet!

Check out the latest San Francisco 49ers vs Los Angeles Rams betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "San Francisco 49ers" with odds of 2.48 from 1 out of 1 users.

The hottest bet types to choose from:

Home Away
San Francisco 49ers
100%
1 out of 1 tipsters

JohnnyBet’s Betting Tips for San Francisco 49ers - Los Angeles Rams by tipsters profit

Our most profitable tipster for this event, skillz00 (ranking at 2008 in overall Profit) is predicting 14.8 in profit by staking 10 on San Francisco 49ers (2.48) in Home Away bet.

skillz00
skillz00
Rank: 2008/2119
Profit: -433.69
Home Away
+148 for San Francisco 49ers
10/10
Estimated profit 14.80

JohnnyBet’s Betting Tips for San Francisco 49ers - Los Angeles Rams by tipsters yield

If you trust yield more than profit, skillz00 (with -16.98% overall yield) gives a prediction to get 14.8 profit by staking 10 on San Francisco 49ers (2.48) in Home Away market.

skillz00
skillz00
Rank: 1509/2119
Yield: -16.98%
Home Away
+148 for San Francisco 49ers
10/10
Estimated profit 14.80

JohnnyBet’s Betting Tips for San Francisco 49ers - Los Angeles Rams by tipsters ODI

These tipsters know how to find best-value bets! skillz00, with an ODI parameter of -65.62 stakes 10 on odds of 2.48 for San Francisco 49ers in Home Away market. It can bag a 14.8 profit.

skillz00
skillz00
Rank: 2102/2119
ODI: -65.62
Home Away
+148 for San Francisco 49ers
10/10
Estimated profit 14.80

The best AI betting tips for San Francisco 49ers vs Los Angeles Rams

What result for San Francisco 49ers vs Los Angeles Rams does artificial intelligence predict? AI calculates that the most likely outcome is a bet on San Francisco 49ers in the Home Away market, at odds of 2.48, with a stake of 10, from skillz00.

skillz00
skillz00
Home Away
+148 for San Francisco 49ers
10/10
Estimated profit 14.80

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next San Francisco 49ers vs Los Angeles Rams game. The top prediction, with 100% of the votes, is a win for San Francisco 49ers (odds of 2.48). While, a victory for Los Angeles Rams (1.56) has collected 0% of the votes.

1 100%
2 0%

San Francisco 49ers vs Los Angeles Rams Betting Tips

Tip 1:
Odds 2.48 for San Francisco 49ers (Home Away)
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