22.09.2025 21:45 • United States • MLB 2025

San Francisco Giants - St. Louis Cardinals Predictions and Betting Tips

San Francisco Giants versus St. Louis Cardinals takes place at 21:45 on 22.09.2025.

San Francisco Giants

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St. Louis Cardinals

Choose your bet!

Check out the latest San Francisco Giants vs St. Louis Cardinals betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "San Francisco Giants" with odds of 1.7 from 1 out of 1 users.

The hottest bet types to choose from:

Home Away

San Francisco Giants

100%

1 out of 1 tipsters

JohnnyBet’s Betting Tips for San Francisco Giants - St. Louis Cardinals by tipsters profit

Our most profitable tipster for this event, Oleg Miami (ranking at 1181 in overall Profit) is predicting 7.0 in profit by staking 10 on San Francisco Giants (1.7) in Home Away bet.

Oleg Miami

Rank: 1181/1528

Profit: -113.33

10/10

Estimated profit 7.00

JohnnyBet’s Betting Tips for San Francisco Giants - St. Louis Cardinals by tipsters yield

If you trust yield more than profit, Oleg Miami (with -2.16% overall yield) gives a prediction to get 7.0 profit by staking 10 on San Francisco Giants (1.7) in Home Away market.

Oleg Miami

Rank: 569/1528

Yield: -2.16%

10/10

Estimated profit 7.00

JohnnyBet’s Betting Tips for San Francisco Giants - St. Louis Cardinals by tipsters ODI

These tipsters know how to find best-value bets! Oleg Miami, with an ODI parameter of -4.79 stakes 10 on odds of 1.7 for San Francisco Giants in Home Away market. It can bag a 7.0 profit.

Oleg Miami

Rank: 1245/1528

ODI: -4.79

10/10

Estimated profit 7.00

The best AI betting tips for San Francisco Giants vs St. Louis Cardinals

What result for San Francisco Giants vs St. Louis Cardinals does artificial intelligence predict? AI calculates that the most likely outcome is a bet on San Francisco Giants in the Home Away market, at odds of 1.7, with a stake of 10, from Oleg Miami.

Oleg Miami

10/10

Estimated profit 7.00

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next San Francisco Giants vs St. Louis Cardinals game. The top prediction, with 100% of the votes, is a win for San Francisco Giants (odds of 1.7). While, a victory for St. Louis Cardinals (2.29) has collected 0% of the votes.

1 100%

2 0%

San Francisco Giants vs St. Louis Cardinals Betting Tips

Tip 1:

Odds 1.7 for San Francisco Giants (Home Away)