28.04.2026 18:00 • South America • Copa Sudamericana 2026

San Lorenzo - Santos FC Predictions and Betting Tips

bet365

San Lorenzo versus Santos FC takes place at 18:00 on 28.04.2026.

San Lorenzo

—

Santos FC

Choose your bet!

Check out the latest San Lorenzo vs Santos FC betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Draw Away" and a predicted result of "San Lorenzo" with odds of +142 from 1 out of 2 users.

The hottest bet types to choose from:

Home Draw Away

San Lorenzo

50%

1 out of 2 tipsters

Both Teams To Score

Yes

100%

2 out of 2 tipsters

JohnnyBet’s Betting Tips for San Lorenzo - Santos FC by tipsters profit

Our most profitable tipster for this event, TipsPro (ranking at 3039 in overall Profit) is predicting 12.1 in profit by staking 10 on Yes (+121) in Both Teams To Score bet. Lider75 on the other hand (ranking at 4052), gives a tip on +121 for Yes (Both Teams To Score) by staking 10 to get an estimated profit of 12.1.

Rank: 3039/3791

Profit: -78.63

10/10

Rank: 3039/3791

Profit: -78.63

10/10

Lider75

Rank: 4052/3791

Profit: -3366.72

10/10

Lider75

Rank: 4052/3791

Profit: -3366.72

10/10

JohnnyBet’s Betting Tips for San Lorenzo - Santos FC by tipsters yield

If you trust yield more than profit, TipsPro (with -2.76% overall yield) gives a prediction to get 12.1 profit by staking 10 on Yes (+121) in Both Teams To Score market. Then, there is Lider75 with -6.62% yield. Giving a tip with 10 stake for Yes (+121) in Both Teams To Score. The estimated profit is 12.1.

Rank: 1516/3791

Yield: -2.76%

10/10

Rank: 1516/3791

Yield: -2.76%

10/10

Lider75

Rank: 2011/3791

Yield: -6.62%

10/10

Lider75

Rank: 2011/3791

Yield: -6.62%

10/10

JohnnyBet’s Betting Tips for San Lorenzo - Santos FC by tipsters ODI

These tipsters know how to find best-value bets! TipsPro, with an ODI parameter of -29.35 stakes 10 on odds of +121 for Yes in Both Teams To Score market. It can bag a 12.1 profit. Lider75 (ODI: -488.86) placing betting tip to get 12.1 profit by putting 10 on Yes (+121) in Both Teams To Score bet.

Rank: 3702/3791

ODI: -29.35

10/10

Rank: 3702/3791

ODI: -29.35

10/10

Lider75

Rank: 4013/3791

ODI: -488.86

10/10

Lider75

Rank: 4013/3791

ODI: -488.86

10/10

The best AI betting tips for San Lorenzo vs Santos FC

What result for San Lorenzo vs Santos FC does artificial intelligence predict? AI calculates that the most likely outcome is a bet on Yes in the Both Teams To Score market, at odds of +121, with a stake of 10, from TipsPro. A bet on Yes (+121) in the Both Teams To Score market with a stake of 10 from Lider75 is another AI favourite.

10/10

Lider75

10/10

Lider75

10/10

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next San Lorenzo vs Santos FC game. The top prediction, with 50% of the votes, is a win for San Lorenzo (odds of +142). While, a victory for Santos FC (+195) has collected 0% of the vote, with 50% predicting a draw (+195).

1 50%

X 50%

2 0%

How to watch San Lorenzo vs Santos FC Live Stream

You can watch San Lorenzo vs Santos FC live at 18:00 on 04-28-2026 thanks to bet365 live streaming services. Check the available options on the global listing below.

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San Lorenzo vs Santos FC Betting Tips

Tip 1:

Odds +142 for San Lorenzo (Home Draw Away)

Tip 2:

Odds +121 for Yes (Both Teams To Score)