17.01.2026 20:00 United States NFL 2025/2026

Seattle Seahawks - San Francisco 49ers Predictions and Betting Tips

Seattle Seahawks versus San Francisco 49ers takes place at 20:00 on 17.01.2026.

Seattle Seahawks
Seattle Seahawks
San Francisco 49ers
San Francisco 49ers

Choose your bet!

Check out the latest Seattle Seahawks vs San Francisco 49ers betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "San Francisco 49ers" with odds of 4.12 from 1 out of 1 users.

The hottest bet types to choose from:

Over/Under 47.5
Over
100%
1 out of 1 tipsters
Home Away
San Francisco 49ers
100%
1 out of 1 tipsters

JohnnyBet’s Betting Tips for Seattle Seahawks - San Francisco 49ers by tipsters profit

Our most profitable tipster for this event, shans2019 (ranking at 2674 in overall Profit) is predicting 24.96 in profit by staking 8 on San Francisco 49ers (4.12) in Home Away bet.

shans2019
shans2019
Rank: 2674/2736
Profit: -602.26
Home Away
+312 for San Francisco 49ers
8/10
Estimated profit 24.96
shans2019
shans2019
Rank: 2674/2736
Profit: -602.26
Over/Under 47.5
+103 for Over
10/10
Estimated profit 10.30

JohnnyBet’s Betting Tips for Seattle Seahawks - San Francisco 49ers by tipsters yield

If you trust yield more than profit, shans2019 (with -2.31% overall yield) gives a prediction to get 24.96 profit by staking 8 on San Francisco 49ers (4.12) in Home Away market.

shans2019
shans2019
Rank: 1043/2736
Yield: -2.31%
Home Away
+312 for San Francisco 49ers
8/10
Estimated profit 24.96
shans2019
shans2019
Rank: 1043/2736
Yield: -2.31%
Over/Under 47.5
+103 for Over
10/10
Estimated profit 10.30

JohnnyBet’s Betting Tips for Seattle Seahawks - San Francisco 49ers by tipsters ODI

These tipsters know how to find best-value bets! shans2019, with an ODI parameter of -9.36 stakes 8 on odds of 4.12 for San Francisco 49ers in Home Away market. It can bag a 24.96 profit.

shans2019
shans2019
Rank: 2470/2736
ODI: -9.36
Home Away
+312 for San Francisco 49ers
8/10
Estimated profit 24.96
shans2019
shans2019
Rank: 2470/2736
ODI: -9.36
Over/Under 47.5
+103 for Over
10/10
Estimated profit 10.30

The best AI betting tips for Seattle Seahawks vs San Francisco 49ers

What result for Seattle Seahawks vs San Francisco 49ers does artificial intelligence predict? AI calculates that the most likely outcome is a bet on San Francisco 49ers in the Home Away market, at odds of 4.12, with a stake of 8, from shans2019.

Home Away
+312 for San Francisco 49ers
8/10
Estimated profit 24.96
Over/Under 47.5
+103 for Over
10/10
Estimated profit 10.30

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Seattle Seahawks vs San Francisco 49ers game. The top prediction, with 100% of the votes is a win for San Francisco 49ers (odds of 4.12). A victory for Seattle Seahawks (1.3) has collected 0% of the votes.

1 0%
2 100%

Seattle Seahawks vs San Francisco 49ers Betting Tips

Tip 1:
Odds 4.12 for San Francisco 49ers (Home Away)
Tip 2:
Odds 2.03 for Over (Over/Under 47.5)
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