22.11.2025 12:00 • United States • NCAA Football 2025

SMU Mustangs - Louisville Cardinals Predictions and Betting Tips

SMU Mustangs versus Louisville Cardinals takes place at 12:00 on 22.11.2025.

SMU Mustangs

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Louisville Cardinals

Choose your bet!

Check out the latest SMU Mustangs vs Louisville Cardinals betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "SMU Mustangs" with odds of 1.62 from 1 out of 1 users.

The hottest bet types to choose from:

Home Away

SMU Mustangs

100%

1 out of 1 tipsters

JohnnyBet’s Betting Tips for SMU Mustangs - Louisville Cardinals by tipsters profit

Our most profitable tipster for this event, GamblingSport19 (ranking at 2063 in overall Profit) is predicting 6.2 in profit by staking 10 on SMU Mustangs (1.62) in Home Away bet.

GamblingSport19

Rank: 2063/2276

Profit: -274.09

10/10

Estimated profit 6.20

JohnnyBet’s Betting Tips for SMU Mustangs - Louisville Cardinals by tipsters yield

If you trust yield more than profit, GamblingSport19 (with -5.16% overall yield) gives a prediction to get 6.2 profit by staking 10 on SMU Mustangs (1.62) in Home Away market.

GamblingSport19

Rank: 1078/2276

Yield: -5.16%

10/10

Estimated profit 6.20

JohnnyBet’s Betting Tips for SMU Mustangs - Louisville Cardinals by tipsters ODI

These tipsters know how to find best-value bets! GamblingSport19, with an ODI parameter of -23.22 stakes 10 on odds of 1.62 for SMU Mustangs in Home Away market. It can bag a 6.2 profit.

GamblingSport19

Rank: 2167/2276

ODI: -23.22

10/10

Estimated profit 6.20

The best AI betting tips for SMU Mustangs vs Louisville Cardinals

What result for SMU Mustangs vs Louisville Cardinals does artificial intelligence predict? AI calculates that the most likely outcome is a bet on SMU Mustangs in the Home Away market, at odds of 1.62, with a stake of 10, from GamblingSport19.

GamblingSport19

10/10

Estimated profit 6.20

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next SMU Mustangs vs Louisville Cardinals game. The top prediction, with 100% of the votes, is a win for SMU Mustangs (odds of 1.62). While, a victory for Louisville Cardinals (2.19) has collected 0% of the votes.

1 100%

2 0%

SMU Mustangs vs Louisville Cardinals Betting Tips

Tip 1:

Odds 1.62 for SMU Mustangs (Home Away)