26.09.2025 14:20 United States MLB 2025

Chicago Cubs - St. Louis Cardinals Predictions and Betting Tips

Chicago Cubs versus St. Louis Cardinals takes place at 14:20 on 26.09.2025.

Chicago Cubs
Chicago Cubs
St. Louis Cardinals

Choose your bet!

Check out the latest Chicago Cubs vs St. Louis Cardinals betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "Chicago Cubs" with odds of 1.58 from 3 out of 6 users.

The hottest bet types to choose from:

Home Away
Chicago Cubs
50%
3 out of 6 tipsters
Over/Under 8.5
Under
100%
1 out of 1 tipsters
Over/Under 10.5
Over
100%
1 out of 1 tipsters

JohnnyBet’s Betting Tips for Chicago Cubs - St. Louis Cardinals by tipsters profit

Our most profitable tipster for this event, teganeMR (ranking at 1222 in overall Profit) is predicting 5.31 in profit by staking 9 on Chicago Cubs (1.59) in Home Away bet. edoard travieso 85 on the other hand (ranking at 1268), gives a tip on 1.55 for Chicago Cubs (Home Away) by staking 10 to get an estimated profit of 5.5. The third most profitable tipster (1341 this season), Oleg Miami estimates to get 13.14 in profit by staking 9 on 2.46 for St. Louis Cardinals in Home Away market.

teganeMR
teganeMR
Rank: 1222/1587
Profit: -108.49
Home Away
-169 for Chicago Cubs
9/10
Estimated profit 5.31
edoard travieso 85
edoard travieso 85
Rank: 1268/1587
Profit: -130.96
Home Away
-182 for Chicago Cubs
10/10
Estimated profit 5.50
Oleg Miami
Oleg Miami
Rank: 1341/1587
Profit: -187.29
Home Away
+146 for St. Louis Cardinals
9/10
Estimated profit 13.14
staruszek
staruszek
Rank: 1523/1587
Profit: -573.06
Home Away
-172 for Chicago Cubs
10/10
Estimated profit 5.80
fizz06
fizz06
Rank: 1591/1587
Profit: -1221.84
Home Away
+146 for St. Louis Cardinals
10/10
Estimated profit 14.60
1 2

JohnnyBet’s Betting Tips for Chicago Cubs - St. Louis Cardinals by tipsters yield

If you trust yield more than profit, edoard travieso 85 (with -2.17% overall yield) gives a prediction to get 5.5 profit by staking 10 on Chicago Cubs (1.55) in Home Away market. Then, there is Oleg Miami with -2.96% yield. Giving a tip with 9 stake for St. Louis Cardinals (2.46) in Home Away. The estimated profit is 13.14. teganeMR (-4.97% yield) picked 1.59 for Chicago Cubs in Home Away market. Staking 9 will bring 5.31 profit if correct.

edoard travieso 85
edoard travieso 85
Rank: 589/1587
Yield: -2.17%
Home Away
-182 for Chicago Cubs
10/10
Estimated profit 5.50
Oleg Miami
Oleg Miami
Rank: 636/1587
Yield: -2.96%
Home Away
+146 for St. Louis Cardinals
9/10
Estimated profit 13.14
teganeMR
teganeMR
Rank: 761/1587
Yield: -4.97%
Home Away
-169 for Chicago Cubs
9/10
Estimated profit 5.31
faro2013
faro2013
Rank: 801/1587
Yield: -5.6%
Home Away
+146 for St. Louis Cardinals
10/10
Estimated profit 14.60
faro2013
faro2013
Rank: 801/1587
Yield: -5.6%
Over/Under 10.5
+135 for Over
10/10
Estimated profit 13.50
1 2

JohnnyBet’s Betting Tips for Chicago Cubs - St. Louis Cardinals by tipsters ODI

These tipsters know how to find best-value bets! fizz06, with an ODI parameter of 105.59 stakes 10 on odds of 2.46 for St. Louis Cardinals in Home Away market. It can bag a 14.6 profit. edoard travieso 85 (ODI: 13.33) placing betting tip to get 5.5 profit by putting 10 on Chicago Cubs (1.55) in Home Away bet. Third in overall ranking (ODI: -4.94), Oleg Miami, chose Home Away market by going with an 9 stake on odds of 2.46 for St. Louis Cardinals, estimating profit of 13.14.

fizz06
fizz06
Rank: 53/1587
ODI: 105.59
Home Away
+146 for St. Louis Cardinals
10/10
Estimated profit 14.60
edoard travieso 85
edoard travieso 85
Rank: 131/1587
ODI: 13.33
Home Away
-182 for Chicago Cubs
10/10
Estimated profit 5.50
Oleg Miami
Oleg Miami
Rank: 1313/1587
ODI: -4.94
Home Away
+146 for St. Louis Cardinals
9/10
Estimated profit 13.14
teganeMR
teganeMR
Rank: 1358/1587
ODI: -7.76
Home Away
-169 for Chicago Cubs
9/10
Estimated profit 5.31
staruszek
staruszek
Rank: 1481/1587
ODI: -23.39
Home Away
-172 for Chicago Cubs
10/10
Estimated profit 5.80
1 2

The best AI betting tips for Chicago Cubs vs St. Louis Cardinals

What result for Chicago Cubs vs St. Louis Cardinals does artificial intelligence predict? AI calculates that the most likely outcome is a bet on Under in the Over/Under 8.5 market, at odds of 1.96, with a stake of 10, from brave73. A bet on Chicago Cubs (1.58) in the Home Away market with a stake of 10 from staruszek is another AI favourite. The third most likely winning bet according to the algorithm is Chicago Cubs in the Home Away market, on which teganeMR is placing 9 at odds of 1.59.

brave73
brave73
Over/Under 8.5
-104 for Under
10/10
Estimated profit 9.60
staruszek
staruszek
Home Away
-172 for Chicago Cubs
10/10
Estimated profit 5.80
teganeMR
teganeMR
Home Away
-169 for Chicago Cubs
9/10
Estimated profit 5.31
edoard travieso 85
edoard travieso 85
Home Away
-182 for Chicago Cubs
10/10
Estimated profit 5.50
Oleg Miami
Oleg Miami
Home Away
+146 for St. Louis Cardinals
9/10
Estimated profit 13.14
1 2

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Chicago Cubs vs St. Louis Cardinals game. The top prediction, with 50% of the votes, is a win for Chicago Cubs (odds of 1.58). While, a victory for St. Louis Cardinals (2.46) has collected 50% of the votes.

1 50%
2 50%

Chicago Cubs vs St. Louis Cardinals Betting Tips

Tip 1:
Odds 1.59 for Chicago Cubs (Home Away)
Tip 2:
Odds 1.96 for Under (Over/Under 8.5)
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