17.04.2026 20:10 • United States • MLB 2026

Houston Astros - St. Louis Cardinals Predictions and Betting Tips

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Houston Astros versus St. Louis Cardinals takes place at 20:10 on 17.04.2026.

Houston Astros

—

St. Louis Cardinals

Choose your bet!

Check out the latest Houston Astros vs St. Louis Cardinals betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "St. Louis Cardinals" with odds of +119 from 2 out of 3 users.

The hottest bet types to choose from:

Home Away

St. Louis Cardinals

67%

2 out of 3 tipsters

Over/Under 8.5

Under

100%

1 out of 1 tipsters

JohnnyBet’s Betting Tips for Houston Astros - St. Louis Cardinals by tipsters profit

Our most profitable tipster for this event, Emi0512 (ranking at 3084 in overall Profit) is predicting 3.57 in profit by staking 3 on St. Louis Cardinals (+119) in Home Away bet. Jose piñero on the other hand (ranking at 3680), gives a tip on +119 for St. Louis Cardinals (Home Away) by staking 10 to get an estimated profit of 11.9. The third most profitable tipster (3783 this season), viveiron estimates to get 10.7 in profit by staking 10 on +107 for Under in Over/Under 8.5 market.

Emi0512

Rank: 3084/3674

Profit: -115.69

3/10

Jose piñero

Rank: 3680/3674

Profit: -672.3

10/10

viveiron

Rank: 3783/3674

Profit: -1277.49

10/10

DaBigBadWolf

Rank: 3873/3674

Profit: -2562.32

10/10

JohnnyBet’s Betting Tips for Houston Astros - St. Louis Cardinals by tipsters yield

If you trust yield more than profit, Emi0512 (with -1.09% overall yield) gives a prediction to get 3.57 profit by staking 3 on St. Louis Cardinals (+119) in Home Away market. Then, there is Jose piñero with -2.79% yield. Giving a tip with 10 stake for St. Louis Cardinals (+119) in Home Away. The estimated profit is 11.9. DaBigBadWolf (-3.54% yield) picked -145 for Houston Astros in Home Away market. Staking 10 will bring 6.9 profit if correct.

Emi0512

Rank: 1278/3674

Yield: -1.09%

3/10

Jose piñero

Rank: 1462/3674

Yield: -2.79%

10/10

DaBigBadWolf

Rank: 1561/3674

Yield: -3.54%

10/10

viveiron

Rank: 1681/3674

Yield: -4.38%

10/10

JohnnyBet’s Betting Tips for Houston Astros - St. Louis Cardinals by tipsters ODI

These tipsters know how to find best-value bets! Jose piñero, with an ODI parameter of 112.71 stakes 10 on odds of +119 for St. Louis Cardinals in Home Away market. It can bag a 11.9 profit. Emi0512 (ODI: -11.55) placing betting tip to get 3.57 profit by putting 3 on St. Louis Cardinals (+119) in Home Away bet. Third in overall ranking (ODI: -371.37), DaBigBadWolf, chose Home Away market by going with an 10 stake on odds of -145 for Houston Astros, estimating profit of 6.9.

Jose piñero

Rank: 75/3674

ODI: 112.71

10/10

Emi0512

Rank: 3377/3674

ODI: -11.55

3/10

DaBigBadWolf

Rank: 3841/3674

ODI: -371.37

10/10

viveiron

Rank: 3876/3674

ODI: -801.28

10/10

The best AI betting tips for Houston Astros vs St. Louis Cardinals

What result for Houston Astros vs St. Louis Cardinals does artificial intelligence predict? AI calculates that the most likely outcome is a bet on St. Louis Cardinals in the Home Away market, at odds of +119, with a stake of 3, from Emi0512. A bet on St. Louis Cardinals (+119) in the Home Away market with a stake of 10 from Jose piñero is another AI favourite. The third most likely winning bet according to the algorithm is Under in the Over/Under 8.5 market, on which viveiron is placing 10 at odds of +107.

Emi0512

3/10

Jose piñero

10/10

viveiron

10/10

DaBigBadWolf

10/10

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Houston Astros vs St. Louis Cardinals game. The top prediction, with 67% of the votes is a win for St. Louis Cardinals (odds of +119). A victory for Houston Astros (-145) has collected 33% of the votes.

1 33%

2 67%

How to watch Houston Astros vs St. Louis Cardinals Live Stream

You can watch Houston Astros vs St. Louis Cardinals live at 20:10 on 04-17-2026 thanks to bet365 live streaming services. Check the available options on the global listing below.

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Houston Astros vs St. Louis Cardinals Betting Tips

Tip 1:

Odds +119 for St. Louis Cardinals (Home Away)

Tip 2:

Odds +107 for Under (Over/Under 8.5)