16.09.2025 18:40 • United States • MLB 2025

Pittsburgh Pirates - Chicago Cubs Predictions and Betting Tips

Pittsburgh Pirates versus Chicago Cubs takes place at 18:40 on 16.09.2025.

Pittsburgh Pirates

—

Chicago Cubs

Choose your bet!

Check out the latest Pittsburgh Pirates vs Chicago Cubs betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "Pittsburgh Pirates" with odds of 1.78 from 1 out of 1 users.

The hottest bet types to choose from:

Home Away

Pittsburgh Pirates

100%

1 out of 1 tipsters

JohnnyBet’s Betting Tips for Pittsburgh Pirates - Chicago Cubs by tipsters profit

Our most profitable tipster for this event, Santiago Rodriguez (ranking at 98 in overall Profit) is predicting 7.8 in profit by staking 10 on Pittsburgh Pirates (1.78) in Home Away bet.

Santiago Rodriguez

Rank: 98/1453

Profit: 45.58

10/10

Estimated profit 7.80

JohnnyBet’s Betting Tips for Pittsburgh Pirates - Chicago Cubs by tipsters yield

If you trust yield more than profit, Santiago Rodriguez (with 2.95% overall yield) gives a prediction to get 7.8 profit by staking 10 on Pittsburgh Pirates (1.78) in Home Away market.

Santiago Rodriguez

Rank: 345/1453

Yield: 2.95%

10/10

Estimated profit 7.80

JohnnyBet’s Betting Tips for Pittsburgh Pirates - Chicago Cubs by tipsters ODI

These tipsters know how to find best-value bets! Santiago Rodriguez, with an ODI parameter of -8.6 stakes 10 on odds of 1.78 for Pittsburgh Pirates in Home Away market. It can bag a 7.8 profit.

Santiago Rodriguez

Rank: 1235/1453

ODI: -8.6

10/10

Estimated profit 7.80

The best AI betting tips for Pittsburgh Pirates vs Chicago Cubs

What result for Pittsburgh Pirates vs Chicago Cubs does artificial intelligence predict? AI calculates that the most likely outcome is a bet on Pittsburgh Pirates in the Home Away market, at odds of 1.78, with a stake of 10, from Santiago Rodriguez.

Santiago Rodriguez

10/10

Estimated profit 7.80

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Pittsburgh Pirates vs Chicago Cubs game. The top prediction, with 100% of the votes, is a win for Pittsburgh Pirates (odds of 1.78). While, a victory for Chicago Cubs (2.11) has collected 0% of the votes.

1 100%

2 0%

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How to watch Pittsburgh Pirates vs Chicago Cubs Live Stream

You can watch Pittsburgh Pirates vs Chicago Cubs live at 18:40 on 2025-09-16 thanks to bet365 live streaming services. Check the available options on the global listing below.

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Pittsburgh Pirates vs Chicago Cubs Betting Tips

Tip 1:

Odds 1.78 for Pittsburgh Pirates (Home Away)