24.09.2026 12:35 United States MLB 2026

Pittsburgh Pirates - St. Louis Cardinals Predictions and Betting Tips

Pittsburgh Pirates versus St. Louis Cardinals takes place at 12:35 on 24.09.2026.

Pittsburgh Pirates
Pittsburgh Pirates
St. Louis Cardinals

Choose your bet!

Check out the latest Pittsburgh Pirates vs St. Louis Cardinals betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "Pittsburgh Pirates" with odds of -161 from 3 out of 6 users.

The hottest bet types to choose from:

Home Away
Pittsburgh Pirates
50%
3 out of 6 tipsters
Over/Under 6.5
Over
100%
2 out of 2 tipsters
Over/Under 4.5
Under
100%
1 out of 1 tipsters

JohnnyBet’s Betting Tips for Pittsburgh Pirates - St. Louis Cardinals by tipsters profit

Our most profitable tipster for this event, henry L (ranking at 16 in overall Profit) is predicting 6.2 in profit by staking 10 on Pittsburgh Pirates (-161) in Home Away bet. Orythree on the other hand (ranking at 1233), gives a tip on -120 for Over (Over/Under 6.5) by staking 10 to get an estimated profit of 8.3. The third most profitable tipster (1646 this season), Tipsters orochisama estimates to get 6.2 in profit by staking 10 on -161 for Pittsburgh Pirates in Home Away market.

henry L
henry L
Rank: 16/1658
Profit: 203.6
Home Away
-161 for Pittsburgh Pirates
10/10
Estimated profit 6.20
Orythree
Orythree
Rank: 1233/1658
Profit: -68.66
Over/Under 6.5
-120 for Over
10/10
Estimated profit 8.30
Tipsters orochisama
Tipsters orochisama
Rank: 1646/1658
Profit: -556.5
Home Away
-161 for Pittsburgh Pirates
10/10
Estimated profit 6.20
Emily1205
Emily1205
Rank: 1657/1658
Profit: -618.2
Home Away
+139 for St. Louis Cardinals
10/10
Estimated profit 13.90
ALEXANDRIA
ALEXANDRIA
Rank: 1688/1658
Profit: -894.22
Over/Under 4.5
+285 for Under
8/10
Estimated profit 22.80
1 2

JohnnyBet’s Betting Tips for Pittsburgh Pirates - St. Louis Cardinals by tipsters yield

If you trust yield more than profit, henry L (with 2.38% overall yield) gives a prediction to get 6.2 profit by staking 10 on Pittsburgh Pirates (-161) in Home Away market. Then, there is Orythree with -0.69% yield. Giving a tip with 10 stake for Over (-120) in Over/Under 6.5. The estimated profit is 8.3. Tipsters orochisama (-3.0% yield) picked -161 for Pittsburgh Pirates in Home Away market. Staking 10 will bring 6.2 profit if correct.

henry L
henry L
Rank: 442/1658
Yield: 2.38%
Home Away
-161 for Pittsburgh Pirates
10/10
Estimated profit 6.20
Orythree
Orythree
Rank: 568/1658
Yield: -0.69%
Over/Under 6.5
-120 for Over
10/10
Estimated profit 8.30
Tipsters orochisama
Tipsters orochisama
Rank: 709/1658
Yield: -3.0%
Home Away
-161 for Pittsburgh Pirates
10/10
Estimated profit 6.20
faro2013
faro2013
Rank: 795/1658
Yield: -4.38%
Home Away
+141 for St. Louis Cardinals
10/10
Estimated profit 14.10
faro2013
faro2013
Rank: 795/1658
Yield: -4.38%
Over/Under 6.5
-120 for Over
10/10
Estimated profit 8.30
1 2

JohnnyBet’s Betting Tips for Pittsburgh Pirates - St. Louis Cardinals by tipsters ODI

These tipsters know how to find best-value bets! Tipsters orochisama, with an ODI parameter of 11.64 stakes 10 on odds of -161 for Pittsburgh Pirates in Home Away market. It can bag a 6.2 profit. Orythree (ODI: 7.73) placing betting tip to get 8.3 profit by putting 10 on Over (-120) in Over/Under 6.5 bet. Third in overall ranking (ODI: -1.42), henry L, chose Home Away market by going with an 10 stake on odds of -161 for Pittsburgh Pirates, estimating profit of 6.2.

Tipsters orochisama
Tipsters orochisama
Rank: 177/1658
ODI: 11.64
Home Away
-161 for Pittsburgh Pirates
10/10
Estimated profit 6.20
Orythree
Orythree
Rank: 217/1658
ODI: 7.73
Over/Under 6.5
-120 for Over
10/10
Estimated profit 8.30
henry L
henry L
Rank: 1318/1658
ODI: -1.42
Home Away
-161 for Pittsburgh Pirates
10/10
Estimated profit 6.20
Emily1205
Emily1205
Rank: 1579/1658
ODI: -15.56
Home Away
+139 for St. Louis Cardinals
10/10
Estimated profit 13.90
ALEXANDRIA
ALEXANDRIA
Rank: 1712/1658
ODI: -243.2
Over/Under 4.5
+285 for Under
8/10
Estimated profit 22.80
1 2

The best AI betting tips for Pittsburgh Pirates vs St. Louis Cardinals

What result for Pittsburgh Pirates vs St. Louis Cardinals does artificial intelligence predict? AI calculates that the most likely outcome is a bet on Pittsburgh Pirates in the Home Away market, at odds of -161, with a stake of 10, from henry L. A bet on Over (-120) in the Over/Under 6.5 market with a stake of 10 from Orythree is another AI favourite. The third most likely winning bet according to the algorithm is Pittsburgh Pirates in the Home Away market, on which Tipsters orochisama is placing 10 at odds of -161.

Home Away
-161 for Pittsburgh Pirates
10/10
Estimated profit 6.20
Over/Under 6.5
-120 for Over
10/10
Estimated profit 8.30
Home Away
-161 for Pittsburgh Pirates
10/10
Estimated profit 6.20
Home Away
+139 for St. Louis Cardinals
10/10
Estimated profit 13.90
Over/Under 4.5
+285 for Under
8/10
Estimated profit 22.80
1 2

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Pittsburgh Pirates vs St. Louis Cardinals game. The top prediction, with 50% of the votes, is a win for Pittsburgh Pirates (odds of -161). While, a victory for St. Louis Cardinals (+137) has collected 50% of the votes.

1 50%
2 50%

Pittsburgh Pirates vs St. Louis Cardinals Betting Tips

Tip 1:
Odds -161 for Pittsburgh Pirates (Home Away)
Tip 2:
Odds -120 for Over (Over/Under 6.5)
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