21.09.2025 14:10 United States MLB 2025

Minnesota Twins - Cleveland Guardians Predictions and Betting Tips

Minnesota Twins versus Cleveland Guardians takes place at 14:10 on 21.09.2025.

Minnesota Twins
Minnesota Twins
Cleveland Guardians

Choose your bet!

Check out the latest Minnesota Twins vs Cleveland Guardians betting picks and predictions chosen by the JohnnyBet Tipsters community. One of the most popular markets to bet on is "Home Away" and a predicted result of "Minnesota Twins" with odds of 2.09 from 2 out of 3 users.

The hottest bet types to choose from:

Home Away
Minnesota Twins
67%
2 out of 3 tipsters
Over/Under 8.5
Over
100%
1 out of 1 tipsters

JohnnyBet’s Betting Tips for Minnesota Twins - Cleveland Guardians by tipsters profit

Our most profitable tipster for this event, Ulsrud (ranking at 1524 in overall Profit) is predicting 7.8 in profit by staking 10 on Cleveland Guardians (1.78) in Home Away bet. faro2013 on the other hand (ranking at 1526), gives a tip on 2.09 for Minnesota Twins (Home Away) by staking 10 to get an estimated profit of 10.9. The third most profitable tipster (1528 this season), Antonhundballl estimates to get 11.3 in profit by staking 10 on 2.13 for Minnesota Twins in Home Away market.

Ulsrud
Ulsrud
Rank: 1524/1515
Profit: -1479.8
Home Away
-128 for Cleveland Guardians
10/10
Estimated profit 7.80
faro2013
faro2013
Rank: 1526/1515
Profit: -1551.1
Home Away
+109 for Minnesota Twins
10/10
Estimated profit 10.90
faro2013
faro2013
Rank: 1526/1515
Profit: -1551.1
Over/Under 8.5
-120 for Over
10/10
Estimated profit 8.30
Antonhundballl
Antonhundballl
Rank: 1528/1515
Profit: -1593.56
Home Away
+113 for Minnesota Twins
10/10
Estimated profit 11.30

JohnnyBet’s Betting Tips for Minnesota Twins - Cleveland Guardians by tipsters yield

If you trust yield more than profit, faro2013 (with -4.52% overall yield) gives a prediction to get 10.9 profit by staking 10 on Minnesota Twins (2.09) in Home Away market. Then, there is Antonhundballl with -5.3% yield. Giving a tip with 10 stake for Minnesota Twins (2.13) in Home Away. The estimated profit is 11.3. Ulsrud (-8.53% yield) picked 1.78 for Cleveland Guardians in Home Away market. Staking 10 will bring 7.8 profit if correct.

faro2013
faro2013
Rank: 714/1515
Yield: -4.52%
Home Away
+109 for Minnesota Twins
10/10
Estimated profit 10.90
faro2013
faro2013
Rank: 714/1515
Yield: -4.52%
Over/Under 8.5
-120 for Over
10/10
Estimated profit 8.30
Antonhundballl
Antonhundballl
Rank: 755/1515
Yield: -5.3%
Home Away
+113 for Minnesota Twins
10/10
Estimated profit 11.30
Ulsrud
Ulsrud
Rank: 906/1515
Yield: -8.53%
Home Away
-128 for Cleveland Guardians
10/10
Estimated profit 7.80

JohnnyBet’s Betting Tips for Minnesota Twins - Cleveland Guardians by tipsters ODI

These tipsters know how to find best-value bets! Antonhundballl, with an ODI parameter of 3357.71 stakes 10 on odds of 2.13 for Minnesota Twins in Home Away market. It can bag a 11.3 profit. Ulsrud (ODI: 63.63) placing betting tip to get 7.8 profit by putting 10 on Cleveland Guardians (1.78) in Home Away bet. Third in overall ranking (ODI: -368.06), faro2013, chose Home Away market by going with an 10 stake on odds of 2.09 for Minnesota Twins, estimating profit of 10.9.

Antonhundballl
Antonhundballl
Rank: 1/1515
ODI: 3357.71
Home Away
+113 for Minnesota Twins
10/10
Estimated profit 11.30
Ulsrud
Ulsrud
Rank: 68/1515
ODI: 63.63
Home Away
-128 for Cleveland Guardians
10/10
Estimated profit 7.80
faro2013
faro2013
Rank: 1531/1515
ODI: -368.06
Home Away
+109 for Minnesota Twins
10/10
Estimated profit 10.90
faro2013
faro2013
Rank: 1531/1515
ODI: -368.06
Over/Under 8.5
-120 for Over
10/10
Estimated profit 8.30

The best AI betting tips for Minnesota Twins vs Cleveland Guardians

What result for Minnesota Twins vs Cleveland Guardians does artificial intelligence predict? AI calculates that the most likely outcome is a bet on Over in the Over/Under 8.5 market, at odds of 1.83, with a stake of 10, from faro2013. A bet on Cleveland Guardians (1.78) in the Home Away market with a stake of 10 from Ulsrud is another AI favourite. The third most likely winning bet according to the algorithm is Minnesota Twins in the Home Away market, on which Antonhundballl is placing 10 at odds of 2.13.

faro2013
faro2013
Over/Under 8.5
-120 for Over
10/10
Estimated profit 8.30
faro2013
faro2013
Home Away
+109 for Minnesota Twins
10/10
Estimated profit 10.90
Ulsrud
Ulsrud
Home Away
-128 for Cleveland Guardians
10/10
Estimated profit 7.80
Antonhundballl
Antonhundballl
Home Away
+113 for Minnesota Twins
10/10
Estimated profit 11.30

See our tipsters predictions!

Discover the JohnnyBet community's betting tips for the next Minnesota Twins vs Cleveland Guardians game. The top prediction, with 67% of the votes, is a win for Minnesota Twins (odds of 2.09). While, a victory for Cleveland Guardians (1.78) has collected 33% of the votes.

1 67%
2 33%

Minnesota Twins vs Cleveland Guardians Betting Tips

Tip 1:
Odds 1.78 for Cleveland Guardians (Home Away)
Tip 2:
Odds 1.83 for Over (Over/Under 8.5)
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